Merja Kokki Selected Research

Oxycodone (Oxycontin)

5/2022	Epidural Oxycodone for Acute Pain.
12/2021	Oxycodone target concentration dosing for acute pain in children.
12/2021	Population pharmacokinetics of oxycodone: Premature neonates to adults.
1/2020	Oxycodone for pain management in the latent phase of labour - A pragmatic trial.
1/2017	Opioid-Induced Bowel Dysfunction in Patients Undergoing Spine Surgery: Comparison of Oxycodone and Oxycodone-Naloxone Treatment.
6/2016	Cytotoxicity of Oxycodone and Morphine in Human Neuroblastoma and Mouse Motoneuronal Cells: A Comparative Approach.
1/2016	Author's Reply to Parsons: "Cytotoxicity of Oxycodone and Morphine in Human Neuroblastoma and Mouse Motoneuronal Cells: A Comparative Approach".
12/2015	A Dose-Finding Study of Dexketoprofen in Patients Undergoing Laparoscopic Cholecystectomy: A Randomized Clinical Trial on Effects on the Analgesic Concentration of Oxycodone.
12/2012	The analgesic concentration of oxycodone with co-administration of paracetamol -- a dose-finding study in adult patients undergoing laparoscopic cholecystectomy.
9/2012	Intravenous oxycodone for pain relief in the first stage of labour--maternal pharmacokinetics and neonatal exposure.

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Merja Kokki Research Topics

Disease

22	Pain (Aches) 01/2021 - 01/2010
9	Postoperative Pain 05/2022 - 05/2012
7	Neoplasms (Cancer) 01/2020 - 05/2016
6	Acute Pain 05/2022 - 05/2012
6	Wounds and Injuries (Trauma) 01/2020 - 05/2012
5	Hypoxia (Hypoxemia) 11/2021 - 01/2019
3	Alzheimer Disease (Alzheimer's Disease) 03/2021 - 05/2016
3	Cataract (Cataracts) 04/2016 - 01/2013
2	Placental Insufficiency 11/2021 - 01/2019
2	Bacterial Infections (Bacterial Infection) 01/2020 - 01/2018
2	Infections 01/2020 - 11/2018
2	Neuroblastoma 06/2016 - 01/2016
2	Fever (Fevers) 01/2010 - 01/2010
1	Body Weight (Weight, Body) 12/2021
1	Respiratory Insufficiency (Respiratory Failure) 12/2021
1	Lung Diseases (Lung Disease) 05/2021
1	Normal Pressure Hydrocephalus 03/2021
1	Breakthrough Pain 01/2021
1	Opioid-Related Disorders (Opiate Addiction) 01/2021
1	Nausea 08/2020
1	Vomiting 08/2020
1	Pneumonia (Pneumonitis) 01/2020
1	Acute Kidney Injury (Acute Renal Failure) 09/2018
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2018
1	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 01/2018
1	Acidosis 02/2017
1	Asphyxia (Suffocation) 02/2017
1	Opioid-Induced Constipation 01/2017
1	Bullous Pemphigoid (Pemphigoid) 01/2017
1	Cognitive Dysfunction 01/2017
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2017
1	Constipation 01/2017
1	Dementia (Dementias) 01/2017
1	Inflammation (Inflammations) 06/2016
1	Memory Disorders (Memory Loss) 05/2016
1	Shoulder Pain 11/2015
1	Post-Dural Puncture Headache 11/2015
1	Birth Weight (Birth Weights) 03/2014
1	Gestational Diabetes (Gestational Diabetes Mellitus) 03/2014
1	Diabetes Mellitus 03/2014
1	Eye Pain 01/2013

Drug/Important Bio-Agent (IBA)

12	Oxycodone (Oxycontin)FDA LinkGeneric 05/2022 - 05/2012
12	Opioid Analgesics (Opioids)IBA 05/2022 - 09/2012
10	Biomarkers (Surrogate Marker)IBA 03/2021 - 05/2016
7	Analgesics (Analgesic Drugs)IBA 02/2018 - 01/2010
3	Fentanyl (Sublimaze)FDA LinkGeneric 01/2021 - 09/2015
3	ProcalcitoninIBA 01/2020 - 01/2018
3	Morphine (MS Contin)FDA LinkGeneric 06/2016 - 05/2012
3	Acetaminophen (Paracetamol)FDA LinkGeneric 12/2012 - 01/2010
2	Nifedipine (Adalat)FDA LinkGeneric 11/2021 - 01/2020
2	Pharmaceutical PreparationsIBA 11/2021 - 05/2012
2	Buprenorphine (Subutex)FDA LinkGeneric 10/2021 - 01/2021
2	Sufentanil (Sufenta)FDA LinkGeneric 08/2020 - 01/2017
2	3-nitrotyrosineIBA 01/2020 - 03/2019
2	Sildenafil Citrate (Viagra)FDA Link 01/2020 - 01/2019
2	CatalaseIBA 01/2020 - 11/2018
2	AutoantibodiesIBA 01/2018 - 01/2017
2	Naloxone (Narcan)FDA LinkGeneric 01/2017 - 05/2012
2	dexketoprofen trometamol (Keral)IBA 07/2016 - 12/2015
2	C-Reactive ProteinIBA 06/2016 - 05/2016
2	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 11/2015 - 01/2010
2	AntipyreticsIBA 01/2010 - 01/2010
2	Ketoprofen (Orudis)FDA LinkGeneric 01/2010 - 01/2010
1	Lactic Acid (Lactate)FDA LinkGeneric 11/2021
1	Oxygen (Dioxygen)IBA 05/2021
1	Hydromorphone (Dilaudid)FDA LinkGeneric 07/2020
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2020
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2019
1	Vasodilator Agents (Vasodilators)IBA 01/2019
1	Lipocalin-2IBA 09/2018
1	Cystatin CIBA 09/2018
1	Immunoglobulin G (IgG)IBA 01/2017
1	Glutathione PeroxidaseIBA 01/2017
1	AutoantigensIBA 01/2017
1	EtoricoxibIBA 07/2016
1	Interleukin-6 (Interleukin 6)IBA 06/2016
1	CytokinesIBA 06/2016
1	InterleukinsIBA 06/2016
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 06/2016
1	Interleukin-10 (Interleukin 10)IBA 06/2016
1	Interleukin-8 (Interleukin 8)IBA 06/2016
1	Adrenal Cortex Hormones (Corticosteroids)IBA 11/2015
1	Non-Narcotic Analgesics (Analgesics, Non Narcotic)IBA 11/2015

Therapy/Procedure

12	Analgesia 05/2022 - 11/2015
5	Laparotomy 01/2020 - 02/2018
2	Epidural Analgesia 05/2022 - 03/2014
2	Therapeutics 05/2021 - 01/2020
2	Pain Management 11/2015 - 01/2013
2	Laparoscopic Cholecystectomy 12/2012 - 05/2012
1	Anesthesia 10/2021
1	Patient-Controlled Analgesia (Analgesia, Patient Controlled) 02/2018
1	Arthroplasty 07/2016
1	Intravenous Administration 06/2016
1	Ophthalmologic Surgical Procedures 04/2016
1	Phacoemulsification 02/2016
1	Intraocular Lens Implantation 02/2016
1	Epidural Blood Patch 11/2015
1	Injections 11/2015
1	Conservative Treatment 11/2015
1	Tonsillectomy 12/2012